@Article{SpindolaZaMaCoLuDa:2017:EvNoCo,
               author = "Spindola, Rolff Ferreira and Zanin, Hudson and Macena, Cleidivan 
                         Silva and Contin, Andr{\'e} and Luz, Rita de C{\'a}ssia Silva 
                         and Damos, Fl{\'a}vio Santos",
          affiliation = "{Universidade Federal do Maranh{\~a}o (UFMA)} and {Universidade 
                         Estadual de Campinas (UNICAMP)} and {Universidade Federal do 
                         Maranh{\~a}o (UFMA)} and {Instituto Nacional de Pesquisas 
                         Espaciais (INPE)} and {Universidade Federal do Maranh{\~a}o 
                         (UFMA)} and {Universidade Federal do Maranh{\~a}o (UFMA)}",
                title = "Evaluation of a novel composite based on functionalized 
                         multi-walled carbon nanotube and iron phthalocyanine for 
                         electroanalytical determination of isoniazid",
              journal = "Journal of Solid State Electrochemistry",
                 year = "2017",
               volume = "21",
               number = "4",
                pages = "1089--1099",
                month = "Apr.",
             keywords = "Graphene oxide, Iron phthalocyanine, Isoniazid, Multi-walled 
                         carbon nanotube oxide.",
             abstract = "A novel platform for electroanalysis of isoniazid based on 
                         graphene-functionalized multi-walled carbon nanotube as support 
                         for iron phthalocyanine (FePc/f-MWCNT) has been developed. The 
                         FePc/f-MWCNT composite has been dropped on glassy carbon forming 
                         FePc/f-MWCNT/GC electrode, which is sensible for isoniazid, 
                         decreasing substantially its oxidation potential to +200 mV vs 
                         Ag/AgCl. Electrochemical and electroanalytical properties of the 
                         FePc/f-MWCNT/GC-modified electrode were investigated by cyclic 
                         voltammetry, electrochemical impedance spectroscopy, scanning 
                         electrochemical microscopy, and amperometry. The sensor presents 
                         better performance in 0.1 mol L\−1 phosphate buffer at pH 
                         7.4. Under optimized conditions, a linear response range from 5 to 
                         476 \μmol L\−1 was obtained with a limit of detection 
                         and sensitivity of 0.56 \μmol L\−1 and 0.023 
                         \μA L \μmol\−1, respectively. The relative 
                         standard deviation for 10 determinations of 100 \μmol 
                         L\−1 isoniazid was 2.5%. The sensor was successfully 
                         applied for isoniazid selective determination in simulated body 
                         fluids.",
                  doi = "10.1007/s10008-016-3451-9",
                  url = "http://dx.doi.org/10.1007/s10008-016-3451-9",
                 issn = "1432-8488",
             language = "en",
           targetfile = "spindola_evaluation.pdf",
        urlaccessdate = "27 abr. 2024"
}